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Updated: Jun 10, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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ハイブリッド型IおよびIIポリケチド合成は,独特な芳香性ポリケチドを生成する

Li Ya Zhao1, Jing Shi1, Zhao Yang Xu1

  • 1State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Life Sciences, Nanjing University, Nanjing 210023, China.

Journal of the American Chemical Society
|October 16, 2024
PubMed
まとめ

研究者らは,タイプIとタイプIIポリケチド合成酵素 (PKS) の新しい組み合わせによって合成された希少な混合芳香ポリケチドであるスピロサイクリンAを発見した. この発見は 複雑なポリケチドを発見し 設計するための新しい道を開きます

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Removing one hydrogen from the intervening CH2 group...
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