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Updated: Jun 10, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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触媒制御化学選択型 γ-C ((sp3) -H 炭酸の乳酸化:メチル対メチレン

Jie-Lun Yan1, Liang Hu1, Yilin Lu1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|October 16, 2024
PubMed
まとめ

カルボキシル酸の化学選択性乳酸化が可能になった. 新しいキノリン-ピリドンリガンドは,メチルまたはメチレンC ((sp3) -H結合の選択的機能化を可能にし,貴重なガンマ-ラクトンを生成します.

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