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Updated: Jun 9, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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アザフィロンの生物触媒合成を可能にする先祖配列再構築

Chang-Hwa Chiang1,2, Ye Wang2, Azam Hussain3

  • 1Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|October 23, 2024
PubMed
まとめ

この研究は,バイオカタリシスのための優れた酵素を開発するための新しいバイオ情報学と祖先の配列再構築 (ASR) 戦略を導入しています. このアプローチは酵素の発見と最適化を加速し,アザフィロンなどの複雑な分子の効率的な合成を可能にします.

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