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Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
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ヒトCYP2C8によるパクリタキセルの水酸化

Dongxiao Yue1, Elvis Wang Hei Ng2, Hajime Hirao1

  • 1Warshel Institute for Computational Biology, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, P. R. China.

Journal of the American Chemical Society
|October 23, 2024
PubMed
まとめ

CYP2C8によるパクリタキセル代謝は非典型的なリバウンドメカニズムを含みます. C7ヒドロキシル群は触媒を助長し,酵素は

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The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
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