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Updated: Jun 9, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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トランスゲリン2は,T細胞の脂質代謝と抗腫瘍機能を守ります

Sung-Min Hwang1,2, Deepika Awasthi1,2, Jieun Jeong3

  • 1Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA.

Nature
|October 24, 2024
PubMed
まとめ

トランスゲリン-2 (TAGLN2) は,脂肪酸の吸収を調節することにより,CD8+ T細胞の代謝と抗癌機能に不可欠です. TAGLN2をT細胞に復元することで,腫瘍によるストレスと闘い,免疫療法の有効性を高めます.

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Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer07:55

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer

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