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Updated: Jun 9, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

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リラックスした配列空間での最適化を使用してスケーラブルなタンパク質設計

Christopher Frank1,2, Ali Khoshouei1,2, Lara Fuβ1,2

  • 1Laboratory for Biomolecular Nanotechnology, Department of Biosciences, School of Natural Sciences Technical University of Munich, 85748 Garching, Germany.

Science (New York, N.Y.)
|October 24, 2024
PubMed
まとめ

この研究は新しい"幻覚"ベースのタンパク質設計方法を導入し 再訓練なしに高品質のタンパク質の背骨と相互作用を効率的に作成します このアプローチは,様々なタンパク質設計の課題に対する幅広い適用性とスケーラビリティを示しています.

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