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Updated: Jun 9, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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プロインタールイキン-18の成熟の原動力としての構造的可塑性

Jeffrey P Bonin1,2,3, James M Aramini1, Lewis E Kay1,2,3

  • 1Departments of Molecular Genetics and Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Journal of the American Chemical Society
|October 24, 2024
PubMed
まとめ

タンパク質のダイナミクスは 機能に不可欠です この研究では,プロ-インタールイキン-18 (プロ-IL-18) の動きが,カスパース結合と成熟を促し,特定の鎖の展開を持つプラスチック構造を明らかにしています.

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