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Updated: Jun 9, 2025

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
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二次性NINJ1の自己抑制は,プラズマ膜の破裂を防ぐ

Sergei Pourmal1, Melissa E Truong1, Matthew C Johnson2

  • 1Department of Physiological Chemistry, Genentech, South San Francisco, CA, USA.

Nature
|October 30, 2024
PubMed
まとめ

細胞膜の破裂によって細胞死を引き起こすニンジュリン-1 (NINJ1) タンパク質は,二重体を形成することによって不活性に保たれています. 細胞解離を制御する新しいメカニズムを明らかにします

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