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Updated: Jun 8, 2025

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection
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Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection

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モポックスウイルスの変種は,ヒトからヒトへの感染が良くなっている

Jacob Smith

    Nature
    |November 2, 2024
    PubMed
    まとめ

    No abstract available in PubMed .

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    Viral Recombination00:57

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    Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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    A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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