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Updated: Jun 8, 2025

Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors
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多様性標的キメラは,腫瘍免疫マイクロ環境を活用した統合免疫療法を可能にします

Feng Lin1, Shenyi Yin2, Zijian Zhang3

  • 1Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; Shenzhen Bay Laboratory, Shenzhen 518055, China.

Cell
|November 6, 2024
PubMed
まとめ

この研究は 癌の免疫療法のための新しいプラットフォームを導入し 複数の免疫細胞を同時に 活性化する単一の薬を作り出します このアプローチは,複雑な腫瘍免疫マイクロ環境をターゲットにすることで,治療の有効性を高めます.

キーワード:
T細胞の誘導体抗体結合体バイオオートゴーナル化学dendritic 細胞のエンガージャー統合免疫療法マルチセル共関与多種性薬剤トリプル・オートゴーナル・リンクヤー腫瘍免疫マイクロ環境

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