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Updated: Jun 8, 2025

Measurements of Physiological Stress Responses in C. Elegans
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酸化ストレス下での2つのF-ボックスタンパク質によるBACH1四次構造デグロンの認識

Shiyun Cao1, Sheena Faye Garcia2, Huigang Shi1

  • 1Department of Pharmacology, University of Washington, Box 357280, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Cell
|November 6, 2024
PubMed
まとめ

酸化ストレスはBACH1タンパク質内の2つのユニークな分解信号を活性化します 2つの異なるE3結合酵素 (FBXO22とFBXL17) は,BACH1を標的として破壊し,複雑なタンパク質の調節を明らかにした.

キーワード:
BACH1 についてBTB についてFBXL17 についてFBXO22 についてSCF についてクリン・リング・リガゼデグロンディマーヘム窒素酸化物酸化ストレスタンパク質の分解四次構造転写因子ユビキチンリガゼ

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