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Updated: Jun 7, 2025

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
08:46

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

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ネイティブサッカライドのステレオセレクティブラジカルC-グリコシレーションのためのC-OH結合活性化

Hao Xie1, Sheng Wang1, Xing-Zhong Shu1

  • 1State Key Laboratory of Applied Organic Chemistry (SKLAOC), College of Chemistry and Chemical Engineering, Lanzhou University, 222 South Tianshui Road, Lanzhou 730000, China.

Journal of the American Chemical Society
|November 15, 2024
PubMed
まとめ

この研究は,C-グリコシドを合成する新しい効率的な方法を導入し,改変されていないサッカリドから直接アノメリックラジカルを生成します. この簡素化されたプロセスは複数のステップを回避し,高いステレオ選択性を持つC-グリコシル化製品を生成します.

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