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Updated: Jun 7, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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ポリケチド合成チオシステインライアゼ領域の構造に関する洞察

Andrew D Steele1,2, Song Meng1, Gengnan Li1

  • 1Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|November 15, 2024
PubMed
まとめ

この研究は,ピリドクサル-5-リン酸 (PLP) の化学反応を用いたチオシステインライアース (SH) ドメインが,ポリケチド合成酵素 (PKS) の組み立てラインに統合され,新しい硫黄を含むポリケチドを生成する方法を示しています.

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