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Updated: Jun 7, 2025

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
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Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

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全炭素四次中心の形成のための鉄触媒クロスエレクトロフィールカップリング

Andria L Pace1, Felix Xu1, Wei Liu1

  • 1Merck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.

Journal of the American Chemical Society
|November 21, 2024
PubMed
まとめ

この研究は,薬剤発見に不可欠な四次炭素センターを合成するための新しい鉄触媒法を導入しています. この新しいアプローチは,生物模倣のSH2メカニズムを使用して,従来のクロスカップリング反応の限界を克服します.

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