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Updated: Jun 6, 2025

Quantitative 3D In Silico Modeling q3DISM of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease
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作者 修正: ガンマ周波数誘導はアミロイド負荷を減らし,ミクログリアを修正する

Hunter F Iaccarino1,2, Annabelle C Singer2,3,4,5, Anthony J Martorell1,2

  • 1Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Nature
|November 26, 2024
PubMed
まとめ

No abstract available in PubMed .

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Amyloid Fibrils03:03

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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