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Updated: Jun 6, 2025

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進行した乳がんにおけるCDK4/ 6阻害剤の早期投与と延期投与

Gabe S Sonke1, Annemiek van Ommen-Nijhof2, Noor Wortelboer3

  • 1Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. g.sonke@nki.nl.

Nature
|November 28, 2024
PubMed
まとめ

SONIA試験では,先進性乳がんの治療において,サイクリン依存性キナーゼ4およびキナーゼ6阻害剤 (CDK4/ 6i) の第一線対第二線投与による有意な効果は認められなかった. これは,すべての患者にとって第一線CDK4/ 6iが必要ではないことを示唆している.

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