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Updated: Jun 5, 2025

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
06:44

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel

Published on: September 8, 2017

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前立腺がんにおける骨髄介護免疫療法耐性の進化

Aram Lyu1,2,3, Zenghua Fan1, Matthew Clark1

  • 1Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.

Nature
|December 5, 2024
PubMed
まとめ

転移性離抵抗性前立腺がん (mCRPC) の患者は,免疫チェックポイント阻害剤 (ICI) に対して抵抗性があります. アデノシンA2A受容体 (A2AR) 阻害を介してSPP1hi- TAMを標的とすることは,この抵抗を克服する見込みを示しています.

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