-LYTACs

Mengke Xu1, Yuxuan Hu1, Jiayan Wu1

  • 1School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457.

まとめ

新しいナノリソソームターゲティングキメラ (ナノ-LYTAC) は,免疫抑制性M2マクロファージを退化させ,がん免疫療法を強化します. このアプローチは腫瘍の微小環境を再プログラムし,臨床前モデルでは腫瘍の成長と転移を抑制します.

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