関連する実験動画

Updated: Jun 5, 2025

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity
04:04

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity

Published on: January 20, 2023

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転置可能な元素のエクソニゼーションは,進化し機能するタンパク質イソフォームの貯蔵庫を生成する

Yago A Arribas1, Blandine Baudon1, Maxime Rotival2

  • 1Institut Curie, PSL University, Inserm U932, Immunity and Cancer, 75005 Paris, France.

Cell
|December 12, 2024
PubMed
まとめ

移植可能な要素 (TEs) は新しいタンパク質イソフォームにスプライスされ,ヒトのタンパク質の多様性を増やすことができます. これらの機能的 TE-spliced isoformsは,表現が低いものの,個体間で保存され,自然選択によって形作られる可能性があります.

キーワード:
クリプティック・スプライスサイトエクソン誕生非正規のタンパク質タンパク質の進化タンパク質イソフォームタンパク質構造プロテオミクスリボソームプロファイリング適用可能な要素アノテーションなしのスプライシング

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