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Updated: Jun 4, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
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Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

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AFMとディープニューラルネットワークを使用してRNAコンフォーマーの構造を決定する

Maximilia F S Degenhardt1, Hermann F Degenhardt1, Yuba R Bhandari1

  • 1Protein-Nucleic Acid Interaction Section, Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

Nature
|December 18, 2024
PubMed
まとめ

複雑なRNA構造を決定することは困難です. 新しい方法であるHORNETは 柔軟なRNA分子の3D形状を明らかにするために 原子力顕微鏡と機械学習を使用し RNA構造生物学を進めている.

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