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Updated: Jun 4, 2025

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
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Published on: March 20, 2014

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生物触媒C-H酸化は,根子の交互結合を満たす:複雑なピペリジン合成を簡素化する

Jiayan He1, Kenta Yokoi2, Breanna Wixted2

  • 1Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, CA, USA.

Science (New York, N.Y.)
|December 19, 2024
PubMed
まとめ

薬剤化学者は ピペリジンのような複雑な3D分子を 効率的に機能させることができます この新しい方法は,新しい薬剤候補の迅速な合成を可能にする,平らな分子のための方法と同様の,生物触媒と根幹のクロスカップリングを組み合わせています.

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Pericyclic reactions are organic reactions that occur via a concerted mechanism without generating any intermediates. The reactions proceed through the movement of electrons in a closed loop to form a cyclic transition state, where rearrangement of the σ and π bonds yields specific products.
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