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細胞RNAはMAVSと相互作用し,抗ウイルスシグナル伝達を促進する

Nandan S Gokhale1, Russell K Sam1, Kim Somfleth1

  • 1Department of Immunology, University of Washington, Seattle, WA.

Science (New York, N.Y.)
|December 19, 2024
PubMed
まとめ

細胞RNAは,ミトコンドリアの抗ウイルスシグナリングタンパク質 (MAVS) と相互作用することで,抗ウイルスシグナリング複合体を組織する. RNAを除去すると,この複合体が破壊され,インターフェロン産生とウイルスの制限が抑制されます.

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