まとめ
呼吸サイクル中の心電量測定のタイミング・熱調和により,精度が向上します. 呼気終了時の測定は,ランダムなタイミングよりも優れた再現性を提供し,重症患者の臨床的有用性を高めます.
科学分野:
- クリティカルケア・メディシン
- 心肺生理学 心肺生理学
- 医療機器技術 医療機器技術について
背景:
- 熱希釈の心臓出力 (CO) の測定は,重症患者の管理に不可欠です.
- シリアルCO測定における重大な変動と劣った再現性は,臨床的有用性を制限する.
- 呼吸サイクル内のCO測定の最適なタイミングは,まだ研究されていない.
研究 の 目的:
- 熱希釈CO測定の再現性に対する呼吸サイクルタイミングの影響を調査する.
- ピークインスピレーション,ピークエクスパレーション,およびランダムな間隔で取られたCO測定値を比較します.
- CO測定技術の最適化のためのエビデンスに基づいた勧告を提供すること.
主な方法:
- 32人の患者 (自発的に呼吸し,機械的に呼吸) の前向きな研究.
- ピークインスピレーション,エンドエクスハレーション,またはランダム呼吸段階で開始された熱希釈CO測定値のランダム比較.
- 測定の再現性を評価するために標準偏差の分析.
主要な成果:
- ピークインスピレーションまたは終息時に開始されたCO測定は,ランダム注射と比較して,標準偏差が著しく小さいことを示しました.
- 特定の呼吸器相へのタイミング測定は,再現性を著しく改善しました.
- ランダムなタイミングの注射により,CO値の変動が大きくなりました.
結論:
- 熱希釈の心臓出力測定は,呼吸サイクルとの関係でタイミングを決めなければなりません.
- 拡張された再現性と臨床的有用性のために,吐出終了時に測定を開始することが推奨されます.
- 呼吸回路のランダムなポイントで熱希釈CO測定を行うのは避けましょう.
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