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The Tongue and Taste Buds00:49

The Tongue and Taste Buds

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The surface of the tongue is covered with various small bumps called papillae, which either distribute what has been ingested (filiform papillae) or contain the sensory taste (or gustatory) receptor cells (fungiform, circumvallate, and foliate papillae). Embedded within each taste-related papilla are the taste buds—clusters of 30 to 100 gustatory receptor cells.
36.4K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

2.8K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
2.8K
Taste Buds and Receptors01:20

Taste Buds and Receptors

1.8K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
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Somatosensation01:33

Somatosensation

36.4K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.4K
Cranial Nerves: Types Part II01:22

Cranial Nerves: Types Part II

1.3K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
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Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

396
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
396

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Updated: Jun 4, 2025

µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo
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µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo

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触覚制御された舌の制御のためのコリキュラーマップ

Brendan S Ito1, Yongjie Gao2, Brian Kardon2

  • 1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA. itobrendan@gmail.com.

Nature
|January 1, 2025
PubMed
まとめ
この要約は機械生成です。

正確な目標行動には 触覚と身体の位置を 統合することが必要です 横側上部のコリキュル (latSC) は,機械感覚運動マップとして機能する,ダイナミックなタッチガイデッドの舌制御に不可欠です.

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Assessment of Spatial Lingual Tactile Sensitivity using a Gratings Orientation Test
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関連する実験動画

Last Updated: Jun 4, 2025

µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo
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µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo

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Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells
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科学分野:

  • 神経科学
  • センサー・モーター統合
  • 動物の行動

背景:

  • 目標に導かれた行動には 触覚情報と 自身の知覚と 動きを統合する必要があります
  • 舌のダイナミックな制御は 噛みつくことや話すことといった行動において 精密な触覚イベントに依存しますが 基礎となる神経回路は不明です

研究 の 目的:

  • ダイナミックなタッチ・ガイデッドの 舌の制御を担当する 神経回路を調査する
  • lateral superior colliculus (latSC) が舌の動きに関する触覚情報と自己感知情報を統合する役割を決定する.

主な方法:

  • マウスの3次元言語運動を分析する高速ビデオ撮影
  • 皮質と皮質下部の機能を評価するための光不活性化実験.
  • LATSCのニューロンの活動を特徴付けるための電気生理学的記録.
  • ウイルス追跡と光学微刺激で 神経経路と機能的組織をマップします

主要な成果:

  • ネズミはタッチと舌の位置を統合し,水漏れが予期せぬ動きをすると,リターンする.
  • LATSCの光不活性化,皮質領域を除いて, 触覚誘導による再定位が損なわれている.
  • latSCニューロンは 機械感覚受容場と舌の位置をコードした.
  • latSCは,言語三性子核からの入力を受け,ライクを狙うための地形図を含んでいます.

結論:

  • 側上コリキュル (latSC) は,ダイナミックなタッチガイデッドの舌制御に重要な役割を果たします.
  • latSCはメカノセンサモーターマップとして機能し 精密な舌の動きのための触覚と自感情報を統合します
  • これらの発見は,知られた視覚運動経路に類似した,触覚による指向行動のためのコリキュラーメカニズムを明らかにしています.