関連する実験動画

Updated: Jun 4, 2025

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
16:16

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

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Gタンパク質結合受容体による陽子検出の分子基礎

Matthew K Howard1, Nicholas Hoppe2, Xi-Ping Huang3

  • 1Tetrad graduate program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Bioengineering and Therapeutic Science, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell
|January 3, 2025
PubMed
まとめ

陽子センサーのGタンパク質結合受容体 (GPCR) は,単一の場所ではなく,残留物のネットワークを使用してpH変化を検出します. この発見により これらの重要な受容体の機能の理解が進んでいます

キーワード:
GPCR についてクリオ・エム陽子プロトンセンシングシグナリング構造

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