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関連する概念動画

Overview of the Axial Skeleton01:09

Overview of the Axial Skeleton

5.0K
The skeleton is subdivided into two major divisions—the axial skeleton and the appendicular skeleton. The axial skeleton forms the vertical, central axis of the body. It includes all of the bones of the head, neck, chest, and back. It protects the brain, spinal cord, heart, and lungs. It also serves as the attachment site for muscles that move the head, neck, and back and for muscles that act across the shoulder and hip joints to move their corresponding limbs.
The axial skeleton of the...
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Articulations of the Vertebral Column01:28

Articulations of the Vertebral Column

1.8K
In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...
1.8K
Axial and Appendicular Muscles01:18

Axial and Appendicular Muscles

1.2K
Skeletal muscles, the key players in our body's movement, can be classified into two groups based on their location and function: axial muscles and appendicular muscles. These classifications reflect the primary roles the muscles play in the body's structure and movement.
Axial Muscles
Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and...
1.2K
Functional Classification of Joints01:09

Functional Classification of Joints

3.8K
Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses  or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...
3.8K
Eccentric Axial Loading in a Plane of Symmetry01:16

Eccentric Axial Loading in a Plane of Symmetry

160
Eccentric axial loading occurs when an axial load is applied away from the centroidal axis of a structural member. This scenario is common in engineering, where structural elements may not be directly aligned due to various design or functional requirements.
160
Introduction to Joints00:58

Introduction to Joints

2.8K
The adult human body usually has 206 bones, and except for the hyoid bone in the neck, each bone is connected to at least one other bone. Joints are the location where bones come together. Many joints allow for movement between the bones. At these joints, the articulating surfaces of the adjacent bones can move smoothly against each other. However, the bones of other joints may be joined by connective tissue or cartilage. These joints are designed for stability and provide little or no...
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関連する実験動画

Updated: Jun 3, 2025

Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice
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Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice

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軸性脊椎関節炎

Victoria Navarro-Compán1, Alexandre Sepriano2, Dafne Capelusnik3

  • 1Department of Rheumatology, University Hospital La Paz, IdiPaz, Madrid, Spain.

Lancet (London, England)
|January 11, 2025
PubMed
まとめ

脊椎関節炎は 慢性的な炎症性疾患で 背中の痛みや硬さを引き起こします 早期の診断と治療 (NSAIDsと先進的な治療を含む) は,不可逆的な損傷を予防し,患者の生活の質を改善するために不可欠です.

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Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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科学分野:

  • 病理学と免疫学
  • 運動器系疾患

背景:

  • 軸性脊椎関節炎 (AxSpA) は,軟骨関節と脊椎に影響する慢性炎症性疾患です.
  • 初期症状には,腰痛と硬直性がありますが,周辺および筋骨外症状も一般的です.
  • 診断は困難で,臨床,実験室 (HLA-B27) と画像検査の結果を組み合わせる必要があります.

研究 の 目的:

  • 軸性脊椎関節炎の概要,その症状,診断上の課題,現在の管理戦略について説明する.
  • 構造的損傷を防ぐために,早期の診断と慢性疾患の活動評価の重要性を強調する.
  • 病気の認知度,診断,患者治療の成果を向上させるための将来の方向性について議論する.

主な方法:

  • 診断のための臨床パターン,検査マーカー (HLA-B27) および画像検査結果 (X線写真,MRI) のレビュー.
  • 国際脊椎関節炎協会 (ASAS) の分類基準における評価の活用
  • Axial Spondyloarthritis Disease Activity Score (ASDAS) のようなツールを用いて,疾患の活性度を評価する.

主要な成果:

  • AxSpAには様々な症状があり,総合的な診断が必要である.
  • 持続的な疾患活動は,不可逆的な構造的損傷と機能的障害と相関する.
  • 現在の管理には,非薬理学的介入と薬理学的治療が含まれており,NSAIDは第一線,生物学的/JAK阻害剤は第二線である.

結論:

  • AxSpAの早期かつ正確な診断は,効果的な管理に不可欠です.
  • 長期的な合併症を緩和するには 病気管理戦略を最適化することが不可欠です
  • 将来の進歩は,病気の認識,診断能力,患者の生活の質を向上させることを目的としています.