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Updated: Jun 2, 2025

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
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Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices

Published on: July 14, 2010

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カチオン性ペプチドは,エンドフィリン媒介のエンドサイトーシスによって記憶喪失を引き起こす

Eric G Stokes1, Jose J Vasquez2, Ghalia Azouz2

  • 1Pharmacology Graduate Program, University of Colorado Anschutz, Aurora, CO, USA.

Nature
|January 15, 2025
PubMed
まとめ

ゼータ抑制ペプチド (ZIP) のようなカチオン性ペプチドは,表面AMPA受容体を取り除き,その既知の標的PKMζとは独立したプロセスで記憶を消去します. この発見は 記憶の変調と喪失の 新しいメカニズムを明らかにします

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