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Updated: Jun 2, 2025

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

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体細胞における突然変異性DNA病変の長期持続

Michael Spencer Chapman1,2, Emily Mitchell1,3,4, Kenichi Yoshida1

  • 1Wellcome Sanger Institute, Hinxton, UK.

Nature
|January 15, 2025
PubMed
まとめ

ヒトの幹細胞に長年存在し,突然変異に大きく貢献するDNAの損傷もあります. 内外の要因による DNAの持続的な損傷は 細胞変異率に影響を与え 血液がんと関連しています

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