関連する実験動画

Updated: Jun 1, 2025

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation
12:42

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation

Published on: November 26, 2014

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Xist の拡散行動と限られた拡散の生体物理的根拠

Mingrui Ding1, Danni Wang2, Hui Chen3

  • 1State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.

Cell
|January 17, 2025
PubMed
まとめ

Xist RNAはHNRNPKによる液体-液体相分離を用いて染色体全体に広がり,静止因子を集約する. この生物学的メカニズムは,Xist RNAを説明する.

キーワード:
HNRNPK についてRGG ドメインRepB についてシストRNAcis-制限された広がりコンデンサ変形性ドロップレット液体-液体相分離Bを繰り返す

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Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

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Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells15:54

Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

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In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will...
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