関連する実験動画

Updated: Jun 1, 2025

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
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Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Published on: January 19, 2015

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HIVカプシドの通過は核孔を裂く

Jan Philipp Kreysing1, Maziar Heidari2, Vojtech Zila3

  • 1Department of Molecular Sociology, Max Planck Institute of Biophysics, Max-von-Laue-Straße 3, 60438 Frankfurt am Main, Germany; IMPRS on Cellular Biophysics, Max-von-Laue-Straße 3, 60438 Frankfurt am Main, Germany.

Cell
|January 18, 2025
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) のカプシドは,細胞に入る際に核孔複合体 (NPC) を破裂する. この経路は,サイクロフィリンAを脱離し,カプシドの円形によってカプシドの整合性を維持します.

キーワード:
CLEM についてHIV ウイルスHIV カプシドHIV核の侵入MDシミュレーションNPC についてSTED についてクリオ・エットインサイト冷凍ET核孔複合体サブトモグラムの平均

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