関連する実験動画

Updated: Jun 16, 2025

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
08:01

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

Published on: May 30, 2012

10.4K

Mettl3-Mettl14-Dnmt1軸による遺伝子発現の微調整 ESCの差異化

Giuseppe Quarto1, Andrea Li Greci1, Martin Bizet1

  • 1Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.

Cell
|January 18, 2025
PubMed
まとめ

METTL3-METTL14複合体は,DNAメチル化 (m6A) とDNAメチル化 (5mC) をDNMT1を誘導することによって結びつける. このエピジェネティック-エピトランスクリプトミックの相互作用は,遺伝子調節と胚幹細胞の分化に不可欠です.

キーワード:
DNAメチル化DNMT1 についてESC についてMETTL14 についてMETTL3 について区分するエピジェネティクスエピトランスクリプトミクス遺伝子発現m ((6) A について

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