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Updated: May 31, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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動的運動解像度に基づく非対称移転によるラセミック2代入キノリンの水素化

Ming-Rong Liang1, Xian Du1, Jian Lin1

  • 1Faculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen 518107, China.

Journal of the American Chemical Society
|January 22, 2025
PubMed
まとめ

この研究は,内循環と外循環の両方のキラルセンターを持つキラルテトラヒドロキノリン (THQ) の合成のための新しい方法を示しています. ダイナミック・キネティック解像度アプローチは,高い収量とステレオ選択性を達成し,医薬品化学の選択肢を拡大します.

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