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Updated: May 31, 2025

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
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Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions

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異なるメカニズムで動作する同じ触媒によって統一されたキラル7つまたは8つ環を形成するエナチオ制御サイクリング

Nicolò Tampellini1, Brandon Q Mercado1, Scott J Miller1

  • 1Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.

Journal of the American Chemical Society
|January 23, 2025
PubMed
まとめ

この研究は,薬剤開発における以前の合成課題を克服し,キラル型中型環を合成するための新しい有機触媒法を導入しています. このアプローチは,固有のキラリティを持つ7つまたは8つあるリングのエナチオセレクティブ形成を可能にする.

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