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Updated: May 30, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
11:31

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model

Published on: August 16, 2019

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新たに発症した1型糖尿病を逆転させるための,Granzyme B-Cleavable T細胞標的バイスペシフィック・セル・ベシクル・コネクター

Yanfang Wang1, Yanping Sun1, Xiuwen Zhang1

  • 1State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Journal of the American Chemical Society
|January 27, 2025
PubMed
まとめ

新しい細胞膀治療は,免疫機能を維持しながらCD8+ T細胞を標的として,新発症型の1型糖尿病 (T1D) を逆転させます. このアプローチは感染リスクを高めることなく,T1D治療の有望で安全な代替手段です.

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Cytotoxic T Cells-mediated Immune Response

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Diabetes Mellitus: Overview and Type I Subtype

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