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Updated: May 30, 2025

Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography
18:45

Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography

Published on: September 2, 2012

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アンドロゲン膜受容体の識別,構造,およびアゴニスト設計

Zhao Yang1, Yu-Qi Ping2, Ming-Wei Wang3

  • 1Key Laboratory Experimental Teratology of the Ministry of Education, New Cornerstone Science Laboratory, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, and Advanced Medical Research Institute, NHC Key Laboratory of Otorhinolaryngology, Qilu hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.

Cell
|January 30, 2025
PubMed
まとめ

アンドロゲン5α- 二酸化テストステロン (5α- DHT) は,筋肉細胞のGPR133膜受容体を活性化し,循環型AMP (cAMP) を増加させることで強さを高める. この発見はアンドロゲン関連の生理学に 新たな治療の道を開きます

キーワード:
GPCR についてアンドロゲンクリオ・エム膜受容体

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Agonists are drugs that interact with specific receptors in the body to produce a biological response. When an agonist binds to a receptor, it activates or enhances the receptor's function, leading to physiological effects. The interaction between agonist drugs and receptors is crucial for their therapeutic action in various medical treatments.
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