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Updated: May 30, 2025

Peptide-based Identification of Functional Motifs and their Binding Partners
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HIV 免疫エバシン Nef は,アロゲニック CAR T 細胞の効能を高める

Karlo Perica1,2, Ivan S Kotchetkov1,3, Jorge Mansilla-Soto1,4

  • 1Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|January 30, 2025
PubMed
まとめ

エンジニアリングされたアロゲニックCAR T細胞は,宿主からの拒絶を回避し,生存率を高め,血液がんの治療可能性を向上させるため,ウイルスの免疫脱出メカニズムを利用します.

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