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Updated: May 5, 2026

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
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Published on: June 20, 2014

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トリアジネーション/IEDDAカスケードモジュール戦略 ピリジン/ピリミジンをチロシンに搭載することでペプチドのスクリーニングと最適化が可能

Quan Zuo1, Xinyi Song2, Jie Yan1

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China.

Journal of the American Chemical Society
|January 31, 2025
PubMed
まとめ

ペプチド改変のための新しいチロシン-1,2,3-トリアジン結合 (YTL) 戦略を開発しました. この方法は,チロシンを含むペプチドの急速な誘導を可能にし,Z8のような潜在的な抗菌剤候補につながる.

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