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Updated: May 29, 2025

Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
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モポックスクラードIbの世界的な感染拡大を抑制する課題

Boghuma K Titanji1, Jason Zucker2

  • 1Division of Infectious Diseases, Department of Medicine, Emory University, Atlanta, GA 30322, USA.

Lancet (London, England)
|February 1, 2025
PubMed
まとめ

No abstract available in PubMed .

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Viral Mutations00:36

Viral Mutations

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A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Viral Recombination

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Overview
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