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Updated: May 29, 2025

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Published on: January 8, 2015

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一つのストップコドンでゲノムで再コードされた生物を設計する

Michael W Grome1,2, Michael T A Nguyen1,2, Daniel W Moonan2,3

  • 1Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.

Nature
|February 5, 2025
PubMed
まとめ

研究者はトランスレーション機能を単一のコドンに圧縮することで,ゲノムで再コードされた生物 (GRO) であるOchreを作りました. この改造されたバクテリアは UAA を 唯一のストップコドンとして使用し 64コドンの不変性遺伝子コードへの道を切り開きます

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