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Updated: May 29, 2025

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
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A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli

Published on: December 9, 2017

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タンパク質の多様化と毒性プロファイルのためのライシンを電子性ヘテロサイクルに変換するアクロライン媒介

Zachary E Paikin1, Benjamin Emenike1, Rajendra Shirke1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|February 7, 2025
PubMed
まとめ

この研究は,タンパク質のライシン残基を選択的に修正し,高度なタンパク質工学とラベリングのためのユニークな構造を作り出す新しい化学反応を導入します. この発見は,タンパク質の相互作用とアクロレイン誘発による変化を理解するのに役立ちます.

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