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Updated: May 28, 2025

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
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Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines

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硫酸オリゴサカライドとグライカンの合成を,エンジニアリングされた変異性6-SulfoGlcNAケースで効率化

Rajneesh K Bains1, Feng Liu1, Seyed A Nasseri1

  • 1Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.

Journal of the American Chemical Society
|February 10, 2025
PubMed
まとめ

研究者は,様々な硫化グリカンを効率的に合成するために,6-SulfoGlcNAcase酵素を設計しました. この突破は 複雑な硫化オリゴサッカリドを様々な生物学的用途に 作り出すための新しい酵素法を提供します

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