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Updated: May 6, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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アプタマー誘導型,水解耐性デオキシオキサノシンは,複雑な環境においても,非エンジニアリングされたタンパク質へのエピトープおよびモエティ選択的結合を可能にします

Hyesung Jo1, Seonmin Ju2,3, Minhye Kim4

  • 1Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Journal of the American Chemical Society
|February 11, 2025
PubMed
まとめ

研究者らはデオキシオキサノシン (dOxa) を含んだアプタマーを使用して精密なタンパク質改変のための新しい方法を開発しました. この技術により,非タンパク質の元素をタンパク質に選択的に結合させ,複雑な生物環境でそれらの機能を高めることができます.

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