大規模な言語モデルを用いた臨床試験の適格性に対する手動対人工知能の予備スクリーニング
Ozan Unlu1,2,3, Matthew Varugheese1,4,5, Jiyeon Shin1,4,5
1Accelerator for Clinical Transformation, Cardiovascular Division, Mass General Brigham, Somerville, Massachusetts.
JAMA
|February 17, 2025
まとめ
No abstract available in PubMed .
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Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...


