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Updated: May 25, 2025

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
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保存されたHIV-1スペーサーペプチド2はマトリックス格子成熟を誘発する

James C V Stacey1,2, Dominik Hrebík1, Elizabeth Nand3

  • 1Department of Cell and Virus Structure, Max Planck Institute of Biochemistry, Martinsried, Germany.

Nature
|February 26, 2025
PubMed
まとめ

スペーサーペプチド2 (SP2) は,ヒト免疫不全ウイルス1型 (HIV-1) マトリックスタンパク質 (MA) の成熟を誘発する. この相互作用は,感染性バイリオンを形成し,標的細胞とのウイルスの融合を促進するために不可欠です.

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