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Updated: Jun 14, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
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プライマリ18O,33P,および溶媒運動同位体効果からSAMHD1の移行状態分析

Ananda K Ghosh1, Daniel P Groom1, Vern L Schramm1

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.

Journal of the American Chemical Society
|February 27, 2025
PubMed
まとめ

研究者は,ヒトのSAMHD1 (無菌アルファモチーフとHD領域を含むタンパク質1) のdATP水解中の移行状態を特徴づけた. この研究は,新しい同位体効果法を使用して,トリフォスフォヒドローラゼの移行状態に関する最初の詳細な化学的洞察を提供します.

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