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Updated: May 24, 2025

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アスピリンは,血小板TXA2のT細胞免疫抑制を制限することによって転移を防ぐ

Jie Yang1, Yumi Yamashita-Kanemaru2, Benjamin I Morris2

  • 1Department of Pathology, University of Cambridge, Cambridge, UK. jy437@cam.ac.uk.

Nature
|March 5, 2025
PubMed
まとめ

アスピリンと他のサイクロオキシゲネーゼ- 1 (COX- 1) 阻害剤は,血小板由来トロンボキサンA2 (TXA2) がT細胞を抑制することを阻害することによって,抗癌免疫を強化します. このメカニズムは 癌の転移に対する免疫療法を改善する 新しい経路を示しています

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