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Updated: Jun 14, 2026

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
11:25

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Published on: March 18, 2017

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効率的なトランスクリプトーム幅のG4マッピングのための超特異的なG-四重体-コリスチン相互作用

Shijiong Wei1, Xiaobo Zhang1, Yilong Feng2

  • 1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.

Journal of the American Chemical Society
|March 6, 2025
PubMed
まとめ

抗生物質のコリスチン (COL) は,パラレルG四重複素 (G4s) に特異的に結合し,それらの結合を引き起こします. この発見により,ヒト細胞内のRNA G4sをマッピングする簡単な方法であるCoRP-seqの開発が可能になった.

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