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肝臓のステラート細胞は,R-スポンジン3によって肝臓の領域化,サイズ,機能を制御する

Atsushi Sugimoto1,2, Yoshinobu Saito1,2,3, Guanxiong Wang4,5

  • 1Department of Medicine, Columbia University, New York, NY, USA.

Nature
|March 13, 2025
PubMed
まとめ

肝臓のステラート細胞 (HSC) は,R-スポンジン3 (RSPO3) を介して肝臓の機能と再生を調節する. HSCまたはRSPO3の喪失は肝臓の健康を損なうし,肝臓疾患を悪化させ,重要なホメオスタティックな役割を果たします.

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