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Updated: May 21, 2025

Measurement of Mitochondrial Oxygen Consumption in Permeabilized Fibers of Drosophila Using Minimal Amounts of Tissue
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ヒトのミトコンドリアのピルバートベーカーの構造とメカニズム

Jiaming Liang1,2,3,4, Junhui Shi1,2,3,4, Ailong Song1,2,3,4

  • 1Fudan University, Shanghai, China.

Nature
|March 18, 2025
PubMed
まとめ

ミトコンドリアのピルバートキャリア (MPC) はピルバートをミトコンドリアに輸送する. Cryo-EM構造は,その交代的なアクセスメカニズムと,抑制剤UK5099がどのように結合し,薬の開発を支援することを明らかにします.

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