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Updated: May 2, 2026

From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins
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From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins

Published on: July 4, 2016

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Mycobacterium tuberculosisCrgAは,細胞膜と環膜βシートの間に挟まれたトランスメブラン領域で二重構造を形成し,他の分裂タンパク質との複数の相互作用を可能にします

Yiseul Shin1,2, Ramesh Prasad3, Nabanita Das2,4

  • 1Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, United States.

Journal of the American Chemical Society
|March 19, 2025
PubMed
まとめ

Mycobacterium tuberculosisの細胞分裂における重要なタンパク質であるCrgAの構造は,固体NMRを用いて決定された. これは,CrgAが細胞壁の合成を促進するために他のタンパク質と二酸化し,相互作用する方法を明らかにします.

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